This link is essential for immunological homeostasis and for the prevention of autoimmune diseases. We are also broadly interested in understanding how cell death signals are propagated. His lab’s current interests include the study of death-receptors and the regulation of T cell activation. Our laboratory investigates the link between apoptotic/cell death signaling and activation of lymphocytes in the immune system. Our research is focused on understanding the mechanisms that control adaptive immune tolerance to self. EDUCATION. This link is essential for immunological homeostasis and for the prevention of autoimmune diseases. Over the last 30 years, Australian artist Craig Walsh has become widely known for his pioneering works including innovative approaches to projection mapping in unconventional sites.
1984 Senior Certificate, Wavell State High School, Brisbane. We have found that this kinase plays a role in regulating thymocyte development and alters the signaling threshold in peripheral T cells. Mixmag Recommended for you. During the course of this research, we have identified a novel serine-threonine kinase called DRAK2 that is differentially regulated during thymocyte development. This work is of high significance to our understanding of immunological tolerance, the means by which the adaptive immune system avoids self-recognition and autoimmunity.
Our work focuses on both viral- and myelin antigen-induced models of multiple sclerosis (MS), and seeks to define specific strategies to promote immune tolerance to stem cell derivatives following transplantation to treat MSInstitute for Immunology, Department of Molecular Biology and BiochemistryThe Experimental Foundations of Modern Immunology by William R. Clark Dr. Walsh is an expert in Immunology and his research focuses on the role apoptotic signal transduction plays in the development, activation and homeostasis of the immune system. A © 2020 UC REGENTS. Current Creative producer, Splendour in the Grass Arts program.
In order to study the role of death-receptor induced apoptosis in T cells, we have generated mice that express inhibitors of certain apoptotic pathways. Our current interests include the study of death-receptors and the regulation of T cell activation. 2014 Craig Walsh: Embedded, Institute of Modern Art, Brisbane. These paradoxical results suggest that T cells utilize similar signal transduction pathways to initiate proliferation and apoptosis and provide a framework for elucidating the homeostatic regulation of T cells that is crucial for a functional immune system. Walsh, Craig, Ph.D. Craig Walsh, Ph.D. 50+ videos Play all Mix - Craig Walsh & Dave Angel Dreamscape 20 YouTube; Andrew Weatherall ... NIGHTMARES ON WAX sunset set in The Lab IBZ - Duration: 1:31:28.
We are concerned primarily with T cells, and how these immune cells normally avoid reaction against self tissues. We are curious about the interaction between T cells and neural stem cells, with an interest in developing approaches to treat autoimmune diseases of the brain such as multiple sclerosisOur research focuses on the role apoptotic signal transduction plays in the development, activation and homeostasis of the immune system. Since this stage is thought to involve apoptosis, we are investigating apoptotic pathways that might contribute to this process. Professor. SELECTED/RECENT SOLO EXHIBITIONS. Professor Research in Lay Terms.
CRAIG WALSH – CV. Our laboratory investigates the link between apoptotic/cell death signaling and activation of lymphocytes in the immune system. A IMMUNOLOGY Department: Molecular Biology & Biochemistry Research Description. Although the specific function of this kinase is unclear, our lab is currently investigating the role of this kinase in T cell development and activation. Dan will explain ideas on how we can do this in as user friendly manner as possible. This adapter protein is involved in activating caspases, cysteine proteases that initiate and execute the death program during apoptosis. Ultimately, our objective is to investigate the paradigms that regulate immune homeostasis through the study of the intersection of apoptotic and growth regulatory pathways.A third area of investigation is on the interaction between T cells and neural stem cells, with the hypothesis that T cell tolerance is essential for the successful transplantation of stem cell derivatives. Craig Walsh is on Facebook.